1. Prevent cardiovascular diseases. If low-density lipoprotein (LDL) is oxidized, the resulting oxidized low-density lipoprotein will block arteries and lead to atherosclerosis. Capsaicin is a potential antioxidant. Capsaicin is an effective vasodilator and diuretic for salt-induced hypertension model mice, and can maintain normal blood pressure by balancing the nervous and hormonal systems. Calcitoningene-related peptide (CGRP) is a peptide substance released by capsaicin-sensitive sensory nerve endings, which is related to cardiovascular diseases, especially hypertension.
2. Prevent and treat digestive tract diseases. Capsaicin-sensitive afferent nerves play an important role in the gastric mucosal defense mechanism. Capsaicin can stimulate afferent nerves and increase the release of CGRP and substance P in the stomach to protect the gastric mucosa. Capsaicin-sensitive sensory nerves play an important role in the mucosal defense mechanism through the regulation of gastric functions such as mucosal blood flow and gastric peristalsis. They not only protect the gastric mucosa when it is damaged, but also help to heal the damage. Capsaicin can stimulate the oral mucosa to increase the secretion of amylase in saliva, reflexively increase gastric motility, increase the activity of digestive enzymes, and improve digestive function.
3. Impact on respiratory diseases. If a person is exposed to 0.5-1.0 ppm chlorine for 15 minutes without a gas mask, it will cause a nasal obstruction reaction. Mice also have a direct nasal obstruction reaction similar to that of humans. Pretreatment with capsaicin can significantly reduce the irritability and nasal obstruction reaction of mice to chlorine.
4. Analgesia. The effect of capsaicin on sensory nerves is that local application of capsaicin can desensitize the body to stimuli such as pain and itching without affecting the mechanical stimulation threshold, such as temperature, pressure or tactile stimulation. Capsaicin can be used as a typical analgesic for the treatment of different pain conditions, which can slow down and improve the pain that patients cannot or rarely control with other methods.
5. Anti-cancer. Capsaicin can change the expression of tumor-related genes. Capsaicin can inhibit the lipid peroxidation reaction of aflatoxin B1 to the liver, thereby reducing its damage to the liver. Damage to the liver by aflatoxin B1. Capsaicin is effective in treating human hepatoma. Capsaicin has an anti-prostate cancer cell effect in men, and capsaicin is expected to become a substitute for chemical drugs for treating prostate cancer.
6. Weight loss. Capsaicin can promote lipid metabolism, dissolve fat, and inhibit fat accumulation in the body. After entering the human body, capsaicin can promote the secretion of neurotransmitters acetylcholine and norepinephrine, and adrenaline can play a more effective weight loss role by sweating and burning fat.
7. Treat frostbite and baldness. Capsaicin can dilate blood vessels, promote microcirculation and hair growth.
8. Other effects. Prurigo is a general term for a group of acute or chronic inflammatory skin diseases. It is a pruritic skin disease that often occurs on the extensor side of the limbs. Its triggering mechanism is still unclear, and most people believe that it may be related to allergic reactions. Capsaicin stimulates nerves to release CGRP and SP, which can effectively treat skin neuroinflammation and prurigo. Capsaicin can enhance the spontaneous discharge activity of renal afferent fibers. Capsaicin has a therapeutic effect on compensatory ovarian hypertrophy (COH) and compensatory ovulation (CO) in adult female mice with uterus removed. Capsaicin has an inhibitory effect on many bacteria and fungi, is safer than chemical preservatives, and has nutritional effects. Chili pepper is a natural preservative with a broad spectrum of antibacterial properties, and is healthy, green and environmentally friendly. Ma pepper has a good anti-fatigue effect.